Open AccessTOPICAL USE OF GREEN PROPOLIS FOR WOUND HEALING: A SYSTEMATIC REVIEW OF THE LITERATURE
Author(s) -
Talita Faraj Faria,
Roberta Faraj Faria,
Ivone Kamada,
Lívia Cristina Lira de Sá Barreto
Publication year - 2022
Publication title -
estima
Language(s) - English
Resource type - Journals
eISSN - 2595-7007
pISSN - 1806-3144
DOI - 10.30886/estima.v20.1135_in
Subject(s) - propolis , cinahl , medicine , wound healing , medline , traditional medicine , systematic review , web of science , dermatology , surgery , meta analysis , pathology , chemistry , nursing , biochemistry , psychological intervention
Objective: To systematically identify the effectiveness of the topical use of green propolis in the healing process of surgical wounds. Methods: Systematic review of the literature that considered the publications available in the databases: National Library of Medicine(PubMed/MEDLINE), LatinAmerican and Caribbean Health Sciences Literature (LILACS), The Cumulative Index to Nursing and Allied Health Literature (CINAHL), and Web of Science. The risk of bias of the studies was analyzed using the Systematic Review Centre for Laboratory animal Experimentation (SYRCLE) tool. Results: The four studies analyzed used green propolis for the healing of surgically made lesions. All the selected studies were of experimental methodology, performed with animals. Two studies (50%) used the ethanolic extract of green propolis (at concentrations of 2.4% and 20%) and the other two studies (50%) used the hydroalcoholic extract of green propolis at 5.0%. Conclusion: The results showed that the topical use of formulated products based on green propolis promoted the healing of skin lesions, since it favored angiogenesis, the proliferation of fibroblasts and, consequently, the synthesis and deposition of collagen, as well as showed antimicrobial activity and showed.