Open AccessAntioxidant and antimicrobial activity of whole seed extracts of Perseaamericana Mill
Author(s) -
C. Rekha,
L.R. Saranya,
R. Karthik,
Vimala Sarojini,
Rajaguru Paramaguru
Publication year - 2016
Publication title -
indian journal of pharmaceutical and biological research
Language(s) - English
Resource type - Journals
ISSN - 2320-9267
DOI - 10.30750/ijpbr.4.4.4
Subject(s) - dpph , chemistry , antibacterial activity , antioxidant , antimicrobial , methanol , agar diffusion test , aqueous solution , food science , traditional medicine , scavenging , antifungal , organic chemistry , biochemistry , bacteria , biology , microbiology and biotechnology , escherichia coli , medicine , gene , genetics
Perseaamericana Mill used in traditional medicine for the treatment of various ailments and has antibacterial, antifungal, anti-viral and wound-healing properties. In the present study, antioxidant and antibacterial activity of different extracts of Perseaamericana Mill were investigated. Antioxidant potential of plant extracts was evaluated by means of total phenolic, total flavonoids content and DPPH radical scavenging activity. The highest phenolic and flanovoid content was observed in methanol extract while the lowest was achieved in aqueous extract. At concentration of 500 SOH g/mL, DPPH radical scavenging activity was found to be highest in methanol extract (70%) and lowest in aqueous extract (51%). Antibacterial activity of different extracts was evaluated by using the disk diffusion method. Highest antibacterial activity was observed with methanol extract against S. pyogenes, while minimum activity was observed with aqueous extract against E.coli.