Open AccessU.V.Spectrophotometric Method development for Capecitabine Eudragit and Chitosan based Microspheres and its Validation
Author(s) -
S. C. Kumbhar,
Vijay R Salunkhe
Publication year - 2013
Publication title -
indian journal of pharmaceutical and biological research
Language(s) - English
Resource type - Journals
ISSN - 2320-9267
DOI - 10.30750/ijpbr.1.3.7
Subject(s) - capecitabine , absorbance , microsphere , chromatography , dosage form , materials science , biomedical engineering , chemistry , medicine , chemical engineering , engineering , colorectal cancer , cancer
A simple, rapid, accurate, precise, and economic Spectrophotometric method for formulated microspheres dosage form has been developed. Capecitabine shows absorbance maximum at different wavelength in different solvents, so absorbance was measured and the same wavelengths used for the estimation of Capecitabine in respective solvents. Capecitabine obey the beer lamberts’ law. Method is validated according to ICH guideline and carried out for analysis of Capecitabine