
Effect Of Intaking High-Fat Diet On White Rat’s (Rattus norvegicus)Blood Lipid Profil
Author(s) -
Made Subawa Harsa
Publication year - 2017
Publication title -
jurnal ilmiah kedokteran wijaya kusuma
Language(s) - English
Resource type - Journals
eISSN - 2580-5967
pISSN - 1978-2071
DOI - 10.30742/jikw.v3i1.36
Subject(s) - cholesterol , lipid profile , obesity , blood lipids , biology , total cholesterol , completely randomized design , medicine , endocrinology , food science , zoology , chemistry
Obesity and metabolic syndrom are characterized by dislipidemia. One of methods that is performed to increase body fat contents is by intaking of high-fat diet. The purpose of this study was to demonstrate the effect of a dietary intake of high-fat on the lipid profile (total cholesterol, HDL, LDL, and triacylglycerol) in white rat (Rattus norvegicus). This research was tested on 30 white rats that were divided into 2 randomized groups, and were treated for 4 weeks. Group 1 (K1) : was treated with standard diet, (K2) : with standard and high-fat diet. The results showed that intaking high-fat diet increases the total cholesterol content, triacylglycerol, LDL cholesterol, and decreases HDL cholesterol content.