Open AccessANTI-BACTERIAL ACTIVITY TEST OF ETHANOL EXTRACT, N-HEXANE FRACTION, ETHYL ACETATE FRACTION AND WATER FRACTION FROM DRAGON FRUIT STEM (Hylocereus polyrhizus) AGAINST METHICILLIN-RESISTANT Staphylococcus aureus (MRSA)
Author(s) -
Indah Sulistyarini,
Diah Arum Sari,
Muhammad Ryan Radix Rahardian
Publication year - 2021
Publication title -
jurnal ilmu kesehatan
Language(s) - English
Resource type - Journals
eISSN - 2614-6703
pISSN - 2355-8032
DOI - 10.30650/jik.v9i2.2284
Subject(s) - ethyl acetate , staphylococcus aureus , antibacterial activity , fraction (chemistry) , chemistry , hexane , ethanol , methicillin resistant staphylococcus aureus , traditional medicine , food science , chromatography , bacteria , biology , organic chemistry , medicine , genetics
The stems of red dragon fruit (Hylocereus polyrhizus) are known to have several antibacterial compounds. The purpose of this study was to determine the antibacterial activity of ethanol extract, n-hexane, ethyl acetate, and water fractions from dragon fruit stems on the growth of Methicillin-resistant Staphylococcus aureus (MRSA), and to determine the types of compounds that are antibacterial. The data on the greatest antibacterial activity was found at a concentration of 30% both in the ethanol extract (1,850cm); n-hexane fraction (1,948 cm); ethyl acetate fraction (1,640 cm) and water fraction (0.884 cm). Meanwhile, the results of contact bioautography showed that the antibacterial compounds of Methicillin-resistant Staphylococcus aureus (MRSA) were flavonoids, saponins, and steroids.