Open AccessUrinary C-peptide Creatinine Ratio and Its Correlation with Parameters of Metabolic Syndrome
Author(s) -
Manoj Gedam,
Debajit Sarma,
Bipul Kumar Choudhury
Publication year - 2021
Publication title -
journal of endocrinology research
Language(s) - English
Resource type - Journals
ISSN - 2630-5224
DOI - 10.30564/jer.v3i2.3451
Subject(s) - creatinine , c peptide , endocrinology , medicine , urinary system , metabolic syndrome , urine , insulin resistance , insulin , diabetes mellitus
To assess the correlation between urinary C peptide creatinine ratio with serum C peptide, serum insulin and its correlation with clinical and biochemical parameters of metabolic syndrome. A total of 100 subjects more than 18 years of age with metabolic syndrome according to ATP III criteria with 100 controls were included in a prospective observational study for a period of 1.5 years. Individual parameters of metabolic syndrome was higher in females with hypertriglyceridemia was most common and hyperglycaemia least common parameter of metabolic syndrome. Fasting urinary C peptide creatinine ratio and Stimulated urinary C peptide correlate significantly with fasting serum C peptide (p 2.7 can be used as a parameter to distinguish individual with and without metabolic syndrome. Urinary C peptide creatinine ratio correlate with serum C peptide and parameters of metabolic syndrome and can be used as a non-invasive simple tool to assess insulin resistance and also to distinguish patients with and without metabolic syndrome.