Open AccessEffects of Exercise on the Pharmacokinetics of Icariin II in Rats
Author(s) -
Xiangbin Kong
Publication year - 2019
Publication title -
journal of advances in medicine science
Language(s) - English
Resource type - Journals
eISSN - 2591-7617
pISSN - 2591-7609
DOI - 10.30564/jams.v2i1.161
Subject(s) - icariin , pharmacokinetics , high performance liquid chromatography , athletes , pharmacology , medicine , absorption (acoustics) , chemistry , physical therapy , chromatography , materials science , alternative medicine , pathology , composite material
High performance liquid chromatography (HPLC) was established to determine the concentration of Icariin II in rats. The time-dependent changes in rats after taking Icariin II were studied, and the main pharmacokinetic parameters were obtained. The main pharmacokinetic parameters of taking the medicine in a quiet state, taking the medicine after half an hour of exercise and taking the medicine after long-term exercise were compared to verify whether the absorption and utilization of the Icariin II were more favorable in the exercise state; The paper has important guiding significance for guiding athletes to safe medication and further development of this drug.