Open AccessEffect of Triclabendazole and Dexamethasone on Ovine Fascioliasis
Author(s) -
Oday K. Luaibi
Publication year - 2013
Publication title -
the iraqi journal of veterinary medicine/al-maǧallaẗ al-ṭibbiyyaẗ al-bayṭariyyaẗ al-’irāqiyyaẗ
Language(s) - English
Resource type - Journals
eISSN - 2410-7409
pISSN - 1609-5693
DOI - 10.30539/iraqijvm.v37i2.277
Subject(s) - triclabendazole , dexamethasone , body weight , feces , biology , flock , pharmacology , zoology , veterinary medicine , medicine , fasciola hepatica , immunology , endocrinology , helminths , microbiology and biotechnology
Thirty sheep in a flock suffering from fascioliasis were selected for the trial . Clinical findings, hematological, biochemical and fecal investigations were conducted. These animals were equally divided into two groups, the 1st group was given the flukecide triclabendazole alone, at a rate of 12mg/kg body weight orally and the 2nd group was given the same dose orally together with dexamethasone at a rate 0.5 mg / kg body weight I/M. Results showed that the 2nd group gave the quickest and the best response in the treatment. This could be explained that the use of corticosteroid assisted the triclabendazole in preventing immune damage and fibroplasias inflicted by the liver flukes beside to improvement metabolic actions of the animal.