Open AccessEffect of Aqueous Extract of Tribulus terrestris orally administration on some Biochemical Parameters in Castrated Male Rabbits
Author(s) -
Abeer Uthman Moosa,
Rasha Hussein Kuba,
Yasser A.H. Al Issa
Publication year - 2012
Publication title -
the iraqi journal of veterinary medicine/al-maǧallaẗ al-ṭibbiyyaẗ al-bayṭariyyaẗ al-’irāqiyyaẗ
Language(s) - English
Resource type - Journals
eISSN - 2410-7409
pISSN - 1609-5693
DOI - 10.30539/iraqijvm.v36i2.499
Subject(s) - tribulus terrestris , aldosterone , alkaline phosphatase , medicine , endocrinology , aqueous extract , chemistry , adult male , traditional medicine , biochemistry , traditional chinese medicine , enzyme , alternative medicine , pathology
The present study is aimed to investigate the influence of an aqueous extract of Tribulus terrestris on some biochemical parameters namely, alkaline phosphatase (ALP), Iron, phosphate (PO4), sodium (Na+), potassium (K+), aldosterone, and cortico steroid in unilateral and bilateral castrated male rabbits. Thirty mature male rabbits which are divided randomly in to six groups. group 1: is control, group2: orally administrated 150 mg / kg / day of an aqueous extract of T. terrestris, group3: is bilateral castrated rabbits received D. W., group4: is bilateral castrated rabbits received (150 mg / kg / day) of the extract, group 5: unilateral castrated rabbits received D. W., group 6 is unilateral castrated rabbits received 150 mg / kg / day of the extract, all doses were given orally every day for 30 days. At the end of the experiment, sera were collected and biochemical tests measured. The results showed a significant (P<0.05) increased in ALP level in group 2 and in PO4 level in group 5 in comparison with group1, while PO4 level tended to be decreased significantly (P<0.05) in group 6 when it compared with group 5. The results also showed a significant(P<0.05) increased in (K+) and (Na+) in group 2 and group 6 in comparison with group1 while there was a significant(P<0.05) decreased in (K+) and (Na+) in group 4 when it compared with group 2. In addition there was a significant (P<0.05) increased in aldosterone concentration in group 6 compared with group 1 and group 2. While there was a significant decreased in cortico steroid concentration in group 3 , 5 and 2 compared with group 1 but the cortico steroid showed a significant (P<0.05) increased in group 6 compared with group 1. There were no significant differences between groups concerning the iron concentration.