Open AccessExperimental infection of Klebsiella pneumoniae in urinary tract of rats and guinea pigs
Author(s) -
Zainab Ismail Ibrahim
Publication year - 2008
Publication title -
the iraqi journal of veterinary medicine/al-maǧallaẗ al-ṭibbiyyaẗ al-bayṭariyyaẗ al-’irāqiyyaẗ
Language(s) - English
Resource type - Journals
eISSN - 2410-7409
pISSN - 1609-5693
DOI - 10.30539/iraqijvm.v32i2.740
Subject(s) - kidney , urine , concomitant , guinea pig , klebsiella pneumoniae , pathological , urinary system , biology , pathology , medicine , physiology , endocrinology , escherichia coli , biochemistry , gene
This work aimed to study the pathological changes induced in theurinary organs after infection with K.pneumoniae. Two laboratory femaleanimal species ,white rat&guinea pig ,were infected by tworoutes,ascending (first group) and direct(intra renal-second group).The infection was examined in different periods through the bacterialculture of urine & kidney samples as well as the pathological changes(grossµscopic) were examined after post mortum.The resultes of both groups showed a positive bacteriologic culture ofthe urine & kidney samples concomitant with the gross andhistopathological changes of the kidneys which revealed different degreesof inflammation between the two groups as well as within the indivisualsof the same group, especially the kidney specimens which showedpyelonephritis in rats & guinea pigs of both infection routes (ascendingand intrarenal