Open AccessSome Pathological Study of Experimental Infection of Blastocystis hominis in Mice
Author(s) -
E. H. AL-Taee
Publication year - 2003
Publication title -
the iraqi journal of veterinary medicine/al-maǧallaẗ al-ṭibbiyyaẗ al-bayṭariyyaẗ al-’irāqiyyaẗ
Language(s) - English
Resource type - Journals
eISSN - 2410-7409
pISSN - 1609-5693
DOI - 10.30539/ijvm.v27i1.1095
Subject(s) - blastocystis , desquamation , diarrhea , pathological , parasite hosting , pathology , biology , lesion , necrosis , stomach , infiltration (hvac) , microbiology and biotechnology , medicine , gastroenterology , feces , world wide web , computer science , physics , thermodynamics
Blastocystis hominis isolated from patients suffering from diarrhea patients (56) in number visited two hospital in Baghdad were cultured on liver infusion broth to infecting laboratory animals. Albino mice (4-6) wks in age were infected with Blastocystis hominis by inculcation and after the appearance of clinical signs (weakness, diarrhea) the mice were killed and pathological studies were done on organs like intestine, stomach and liver, the lesion showed desquamation of mucosa, severe infiltration of inflammatory cells specially around the parasite, this lesion was more severe in large intestine from the other organs.
The parasite was seen in liver cells and appeared with different stages of growth and replication causing vaculation and necrosis in the hepatocyte.