Open AccessFREQUENCE OF JUXTAGLOMERULAR GRANULATED CELIS IN DEHYDRATED AND SODIUM-LOADED MICE
Author(s) -
Imad Matloub Dally Al-Ani,
Merza H. Homady
Publication year - 2022
Publication title -
the iraqi journal of veterinary medicine/al-maǧallaẗ al-ṭibbiyyaẗ al-bayṭariyyaẗ al-’irāqiyyaẗ
Language(s) - English
Resource type - Journals
eISSN - 2410-7409
pISSN - 1609-5693
DOI - 10.30539/ijvm.v21i1.1246
Subject(s) - juxtaglomerular apparatus , renin–angiotensin system , nephron , sodium , chemistry , dehydration , macula densa , kidney , endocrinology , medicine , biology , biochemistry , organic chemistry , blood pressure
Fifteen albino mice were subjected to three days dehydration and fifteen albino mice were given 1% NaCl in their drinking water. Control animals were given drinking water
All animals were sacrificed and kidneys were fixed in different fixatives and processed for light microscopy
Section were stained for juxtaglomerular cells demonstration and the juxtaglomerular index (GI) and percentage of granulated nephron(%GN) were calculated. Kidneys from dehydrated and sodium-loaded animals showed significant decrease in both JGI and % GN and was discussed in relation to renin secretion and release.