Open AccessThe Anti-Inflammatory Effect of Vitamin K in Aging
Author(s) -
Zainab Nazar Hasan Anber
Publication year - 2021
Publication title -
mağallaẗ ibn al-haytam li-l-ʻulūm al-ṣirfaẗ wa-al-taṭbīqiyyaẗ/ibn al-haitham journal for pure and applied sciences
Language(s) - English
Resource type - Journals
eISSN - 2521-3407
pISSN - 1609-4042
DOI - 10.30526/34.2.2608
Subject(s) - inflammation , pathogenesis , signal transduction , antioxidant , oxidative stress , vitamin c , vitamin d and neurology , vitamin , immunology , chemistry , biology , biochemistry , endocrinology
Vitamin K is a fundamental enzymatic co-factor implicated in the carboxylation of several vitamin K dependent proteins involved in the pathogenesis of certain age – related diseases. Inflammation is realized as an important factor in such diseases. Vitamin K is recognized to play an anti-inflammatory behavior that is distinct of its action as an enzymatic co- factor by suppressing many signaling pathways mainly the nuclear factor κB (NF-κB) signal transduction pathway. As well as to play a role as an antioxidant versus the generation of reactive oxidative species (ROS). The purpose of this review is to focus on the protective function of vitamin K as an anti-inflammatory agent in these age- associated diseases. And the importance of vitamin K complement as a protective nutrient in aging.