Open AccessEffect of Metformin and Glimepiride Treatment on Some Biochemical Parameters in Diabetic Male Patients with Chronic Renal Failure
Author(s) -
Ali Mohammed Abbed
Publication year - 2019
Publication title -
mağallaẗ ibn al-haytam li-l-ʻulūm al-ṣirfaẗ wa-al-taṭbīqiyyaẗ/ibn al-haitham journal for pure and applied sciences
Language(s) - English
Resource type - Journals
eISSN - 2521-3407
pISSN - 1609-4042
DOI - 10.30526/32.2.2137
Subject(s) - medicine , hyperkalemia , glimepiride , endocrinology , calcium , chronic renal failure , potassium , serum glucose , metformin , diabetes mellitus , creatinine , chemistry , organic chemistry
The present study was included a measurements of fasting serum glucose, total protein, potassium, and calcium levels in the sera of 25 diabetic male patients suffer from chronic renal failure; their ages range were (32-75) and compared them with 25 healthy males as control group. The aim of this study was to study the effects of antidiabetic drugs on some biochemical parameters such as fasting serum glucose, serum total protein, serum potassium and calcium. The current results demonstrated a hyperkalemia in patients and this increasing of potassium is significantly (p = 0.03), but calcium level showed no significant variations ( p>0.05 ), and serum total protein was significantly decreased in patients as compared to the controls( p = 0.0002 ).