Open AccessUrine Bacteriology in Post-Kidney Transplant Patients with Double-J Stents
Author(s) -
Sherifatu Abu,
Martin Igbokwe,
OO Olatise,
Maryann Okafor,
So A,
AR Adetunbi
Publication year - 2021
Publication title -
annals of health research
Language(s) - English
Resource type - Journals
ISSN - 2536-6149
DOI - 10.30442/ahr.0704-04-146
Subject(s) - medicine , kidney transplantation , urinary system , transplantation , nitrofurantoin , surgery , urine , urology , incidence (geometry) , gastroenterology , antibiotics , antibiotic resistance , biology , microbiology and biotechnology , physics , optics
Background: Kidney transplantation is the gold standard treatment modality for patients with end-stage renal disease. Ureteric stenting is commonly used during kidney transplantation to reduce the incidence of ureteric complications post-transplantation. The presence of ureteric stents could be complicated by bacterial colonisation and urinary tract infections.
Objective: To identify the urinary flora in patients with double-J stents following kidney transplantation and establish bacteria colonisation and their antimicrobial susceptibility.
Methods: Over one-year, single urine samples of consecutive 100 post-renal transplant patients were subjected to bacteriologic analysis. Early morning midstream urine was obtained into a sterile bottle from all the participants for laboratory analysis.
Results: The mean age of post kidney transplantation patients was 47.6 ±12.3 years. Hypertension and diabetes were the commonest co-morbidities associated with End-Stage-Renal-Disease (ESRD), accounting for 61% and 28%, respectively. E. coli was the commonest isolate (70.4%). Microbiological evidence of Urinary Tract Infection (UTI) revealed by pyuria (pus cells >4/HPF) was found in 40.9%. Tigecycline, nitrofurantoin and tetracycline showed the highest sensitivity pattern in 9%, 8% and 8%, respectively, with significant resistance against cephalosporins and fluoroquinolones.
Conclusion: The fourth week of double-J ureteric stent insertion in kidney transplant recipients showed a high incidence of urinary bacterial colonisation.