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Brain-derived neurotrophic factor in blood increases transiently after single sessions of moderate intensity exercise in obese females
Author(s) -
Slamet Raharjo,
Ahmad Syahru Mubarok Harisman,
Olivia Andiana,
Yualita Putri Pamungkas
Publication year - 2021
Publication title -
jurnal sportif
Language(s) - English
Resource type - Journals
eISSN - 2548-7833
pISSN - 2477-3379
DOI - 10.29407/js_unpgri.v7i3.16372
Subject(s) - medicine , intensity (physics) , morning , brain derived neurotrophic factor , exercise intensity , treadmill , venous blood , blood sampling , analysis of variance , endocrinology , neurotrophic factors , blood pressure , heart rate , physics , receptor , quantum mechanics
This study aimed to analyze the increase in serum BDNF levels after moderate-intensity exercise in obese females. This study used the True-Experimental method with the Randomized Control Group Pre-test-Post-test design. A total of 14 obese female adolescents aged 19-24 years participated in this study and were divided into two groups, i.e., the control group (CG, n=7) and the moderate-intensity exercise group (MIEG, n=7). The exercise was performed with an intensity of 64 – 76 HRmax for 40 minutes using a Richter Treadmill (4.0 HP DC). Moderate-intensity exercise was carried out in one intervention. Blood sampling was carried out before and after moderate-intensity exercise on the cubital vein as much as 3 ml. Examination of serum BDNF levels using the ELISA method.  The results of statistical analysis show that the mean pre-test serum BDNF levels were CG (258.66±27.11 pg/mL), MIEG (252.48±23.17 pg/mL), and (p=0.865). The mean post-test serum BDNF levels were CG (236.22±20.83 pg/mL), MIEG (497.73±59.55 pg/mL), and (p=0.001). The mean delta of serum BDNF levels on CG (-22.43±26.04), MIEG (245.25±61.57 pg/mL), and (p=0.002). Based on the study results, it is concluded that a single session of moderate-intensity exercise in the morning increases serum BDNF levels in obese females. 

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