Open AccessAtypical Neuroleptic Malignant Syndrome Induced by Low Dose Quetiapine in a Patient Treated with Donepezil
Author(s) -
Elçin Özçelik Eroğlu,
Mevhibe İrem Yıldız,
M. Kâzım Yazıcı
Publication year - 2021
Publication title -
nöropsikiyatri arşivi
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 14
ISSN - 1309-4866
DOI - 10.29399/npa.27421
Subject(s) - neuroleptic malignant syndrome , quetiapine , muscle rigidity , medicine , donepezil , pediatrics , intensive care medicine , psychiatry , dementia , anesthesia , schizophrenia (object oriented programming) , disease
Neuroleptic malignant syndrome is a rare idiosyncratic drug reaction that causes morbidity and mortality. Although muscle rigidity and fever are accepted as major symptoms, there is no consensus on the diagnostic criteria. This flexibility in diagnostic criteria allows for the diagnosis of atypical cases. Keeping in mind that neuroleptic malignant syndrome may also occur with the use of low doses of atypical antipsychotics is important for making the diagnosis quickly and reducing the risk of morbidity and mortality. In this report, we aim to present a case with atypical neuroleptic malignant syndrome associated with the use of very low dose quetiapine and discuss the risk factors that facilitate its emergence.