Open AccessInflammation and Oxidative Stress in Deficit Schizophrenia
Author(s) -
Ferdi Köşger,
Semra Yiğitaslan,
Altan Eşsizoğlu,
Gülcan Güleç,
Reyhan Dağ Karataş,
Sinem Sevİl DeĞİrmencİ
Publication year - 2020
Publication title -
nöropsikiyatri arşivi
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 14
ISSN - 1309-4866
DOI - 10.29399/npa.24966
Subject(s) - oxidative stress , proinflammatory cytokine , inflammation , medicine , schizophrenia (object oriented programming) , tumor necrosis factor alpha , endocrinology , pon1 , interleukin , immunology , cytokine , biology , psychiatry , biochemistry , gene , genotype
Differences in parameters related to inflammatory and oxidative stress in deficit (DS) and nondeficit schizophrenia (non-DS) may support the DS/non-DS categorization of schizophrenia. For DS patients, non-DS patients, and for healthy controls, this study aims to evaluate the serum levels of: proinflammatory cytokines of interleukin (IL) 1β, tumor necrosis factor (TNF) α, Interferon (IFN) γ, IL-12, and IL-17; anti-inflammatory cytokines of IL-10, IFN-α, and transforming growth factor (TGF) β; and antioxidant biomarkers of paraoxonase1 (PON1) and Total Antioxidant Capacity (TAOC).