Open AccessClinical features of the patients with Neuromyelitis Optica Spectrum Disorder
Author(s) -
Arman Çakar,
Canan Ulusoy,
Tuncay Gündüz,
Cem İsmail Küçükali,
Murat Kürtüncü
Publication year - 2019
Publication title -
nöropsikiyatri arşivi
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 14
ISSN - 1309-4866
DOI - 10.29399/npa.23555
Subject(s) - neuromyelitis optica , multiple sclerosis , medicine , optic neuritis , spectrum disorder , demyelinating disorder , cerebrospinal fluid , clinically isolated syndrome , white matter , hyperintensity , central nervous system , acute disseminated encephalomyelitis , magnetic resonance imaging , pathology , pediatrics , immunology , radiology , psychiatry
Neuromyelitis optica spectrum disorder (NMOSD) is an inflammatory, demyelinating syndrome of the central nervous system (CNS) that predominantly affects the spinal cord and optic nerves. Since it was first described, new information about the pathophysiology gained momentum with the discovery of an antibody against Aquaporin-4, a water channel protein that is predominantly found in the astrocytes. In our study, we evaluated the clinical features of NMOSD and clinically related CNS disorders.