Open Accessessential oil; lavender; antimicrobial activity; bioactive compound; GC-MS; Mycobacterium smegmatis.
Author(s) -
María del Rayo Camacho-Corona,
Patricia C. Esquivel-Ferriño,
Aldo F. Clemente-Soto,
Mayela Y. Ramírez-Cabriales,
Elvira GarzaGonzález,
Laura Álvarez
Publication year - 2017
Publication title -
journal of the mexican chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.172
H-Index - 22
ISSN - 2594-0317
DOI - 10.29356/jmcs.v58i4.52
Subject(s) - decanal , antimicrobial , essential oil , mycobacterium tuberculosis , chemistry , citrus × sinensis , palmitic acid , tuberculosis , microbiology and biotechnology , traditional medicine , food science , medicine , biology , fatty acid , biochemistry , pathology , orange (colour)
Tuberculosis (TB) is a great cause of morbidity and mortality around the world. The increasing incidence of multidrug-resistant (MDR) Mycobacterium tuberculosis and co-infection TB-AIDS led to the need to develop new TB drugs, and plants could be a source of them. The hexane extract of Citrus sinensis with anti-TB activity was analyzed by GC-MS. This analysis showed the presence of 40 volatile components, including monoterpenes (81.74%), sesquiterpenes (1.32%), fatty acids (1.15%), and some other oxygenated non-aromatic compounds (15.73%). Some identified compounds were tested against M. tuberculosis H37Rv, and one clinical isolated MDR M. tuberculosis strain. Results showed that palmitic acid, decanal, caryophyllene oxide, and cis -limonene oxide contributed to the anti-TB activity of hexane extract of C. sinensis peel.