ORAL SUBMUCOUS FIBROSIS

Objectives: To compare the efficacy of topical Triamcinolone 0.1% withClobetasol 0.05% in the known cases of Oral Submucous Fibrosis presenting with burningsensations. Study Design: Cross sectional hospital based study. Setting: Department ofOral & Maxillofacial Surgery, Isra Dental College, Isra University Hospital, Hyderabad. Period:Six months. Materials and Methods: A sample of 50 patients was selected through nonprobabilitypurposive sampling according to inclusion and exclusion criteria. 50 patients withOral Submucous Fibrosis were divided into two groups, Group A and Group B, each having25 patients. The pain was measured by the visual analog scale on the scale of 1-10. Patientswere divided into Groups ‘A’ (Triamcinolone 0.1%) and ‘B’ (Clobetasol 0.05%). Patients wereadvised to use the gel twice a day for 3 weeks on the affected mucosal surfaces and were alsoadvised to avoid swallowing for some minutes and not to drink or eat for at least 1 hour after theapplication of drug. Patients were recalled for follow up to record any improvements in burningsensations after the application of the drug. Results: It was seen that both topical drugs werebeneficial in controlling the burning pain in Oral Submucous Fibrosis in the 3 weeks duration,however Clobetasol was better than Triamcinolone, as measured by more rapid control of painby week 1. Conclusion: It is concluded that the efficacy of both topical oral drugs were usefulin diminishing pain and decreasing the burning sensations. However, Clobetasol has to someextent better effectiveness in reducing the burning sensation in patients suffering with OralSubmucous Fibrosis.