COLORECTAL CANCER

Objectives: To determine the changing clinicopathological pattern anddistribution of colorectal cancer in our setup, highlighting future planning and designing forits prevention. Study Design: A retrospective study. Place and Duration: Department ofSurgery, Chandka Medical College and LINAR, Larkana from January 2012 to December 2016.Methodology: All the diagnosed cases of colorectal cancer were included in our study. Therecords analyzed for age, gender, clinical presentation, socioeconomic status, risk factors,histopathological variable types, site of distribution, tumor grading & staging based on TNM.The method of treatment & surgical procedures performed, were also recorded. Statistics datawas entered and analyzed by SPSS version 17. Results: 363 diagnosed cases of colorectalcancer were registered from January, 2012 to December, 2016. 211 (58. %) were male and 147(40.9%) female, with ratio of 1.3:1. Age ranged between 17 to 88 years with mean age of 56 +12. 217 patients were > 50 years, while 146 < 50 years. The predominant subsite distributionwas found in rectum & recto sigmoid junction in 205 cases (56.49%). Majority of cases belong tolow socioeconomic class with Duke’s B and C stages (45.73%. and 39.11%). The mortality ratewas observed in 12.9%, however 30% of patients were not returned for follow-up. Conclusion:Colorectal cancer is shown rising higher up and vated cancer was found increasing in incidenceamong young population < 50 years. There is a need of early detection, to reduce the numberof CRC in future.