Open AccessCIRRHOSIS
Author(s) -
Afroz Saleem Kazi,
Aftab Abbasi,
Saz
Publication year - 2018
Publication title -
the professional medical journal/the professional medical journal
Language(s) - English
Resource type - Journals
eISSN - 2071-7733
pISSN - 1024-8919
DOI - 10.29309/tpmj/2018.25.01.538
Subject(s) - medicine , lamina propria , cirrhosis , gastroenterology , gastric mucosa , endoscope , antrum , inclusion and exclusion criteria , stomach , pathology , surgery , alternative medicine , epithelium
Objectives: To investigate the histological changes in gastric mucosa of livercirrhosis patients. Study design: Cross sectional study. Place and Duration: Department ofAnatomy and Medicine, Gastroenterology unit, Isra University Hospital (June to December2012). Subjects and Methods: 85 diagnosed cases of liver cirrhosis were selected accordingto inclusion and exclusion criteria. Specimen of 2 mm thickness was taken by punch biopsyfrom gastric body and antrum by endoscope. Tissues were fixed in 10% formaldehyde, 3-5 μsections were stained with H & E for microscopy. Data was analyzed on SPSS version 21.0.Results: Age (mean ±SD) was noted as 47±11.5 years. Of 85, 56 (65.8%) were male and29 (34.1%) female. Frequency of mild, moderate, severe and no gastropathy were notedin 52.94%, 34.12%, 4.71%, and 8.24% respectively. 9.4% of cases show capillary dilationand edematous lamina propria. Conclusion: Microscopy shows gastropathy in majority ofspecimens. Thick gastric mucosa, increased gland size and mucosa capillary dilation wasnoted.