Open AccessSYSTEMIC LUPUS ERYTHEMATOSUS;
Author(s) -
Muhammad Afzal Hamdani,
Khalid Parvez,
Faisal Naseeb,
Umair Afzal,
- Bashiruddin,
Joseph Hope Cal,
Sajjad Hussain
Publication year - 2017
Publication title -
the professional medical journal/the professional medical journal
Language(s) - English
Resource type - Journals
eISSN - 2071-7733
pISSN - 1024-8919
DOI - 10.29309/tpmj/2017.24.01.479
Subject(s) - medicine , high resolution computed tomography , pleural effusion , rheumatology , hypersensitivity pneumonitis , atelectasis , pulmonary function testing , lung , radiology
Systemic lupus erythematosus (SLE), is a multifactorial, complex etiologicaldisorder, characterized by inflammation and involvement of multiple organ systems includinglungs. Objective: 1-To evaluate whether high resolution computed tomography (HRCT) helpsin the diagnosis of pulmonary manifestations of SLE. 2-To study the pattern and extent of lunginvolvement using HRCT. Design: A Prospective cross - sectional clinical study. Period: Fouryears, July 2012 to June 2016. Setting: King Khalid University Hospital (KKUH) King SaudUniversity (KSU), Rheumatology division Department of Medicine. Methods: This study included113 patients attending outpatients or admitted as inpatients having respiratory symptomsand diagnosed as SLE according to American College of Rheumatology (ACR) classificationcriteria. Chest X- ray, pulmonary function tests, and HRCT chest were done. Investigationsto detect other organ involvement were done. Pregnant females and patients having otherconnective tissue or occupational diseases were excluded. Results: Of the total 113 patients102 were female and 11 males. Age of patients was 37.1 ±13.0 years. The HRCT abnormalitieswere pleural effusion, pleural thickening, atelectasis, ground glass opacities including nonspecificinterstitial pneumonitis (NSIP) and usual interstitial pneumonitis (UIP), pulmonaryarterial hypertension, pulmonary embolism and hilar lymphadenopathy. Conclusion: Variouspulmonary manifestations are present in a significant number of symptomatic SLE patients anda variety of HRCT patterns can be seen to diagnose and treat them.