COMMON HUMAN PATHOGENS

Background: Due to easy availability or excess to antibiotics people usuallystart antibiotic without consulting doctors when they are suffering from illness and as they werefeeling well they discontinue the treatment and as a result these bacteria become resistantto those antibiotics which are inadequately used. Also most of the antibiotic have side effectthat also produce undesirable effect so after considering all of these issues we want toexplore natural compounds for their antimicrobial activity as these compounds have no sideeffect and cost effective as well. Objectives: We analyzed the antimicrobial activity of ginger(ZINGIBER OFFICINALE) against common human pathogens. Study design: Experimentalstudy. Place and duration of study: All clinical isolates were identified at BUMDC (BahriaUniversity Medical and Dental College) Microbiology Lab (Karachi) by standard biochemicalmethods. Study conducted between april2015-nov 2015. Material & Methods: Staphylococcusaureus, Pseudomonas, Vibrio cholera and E.Coli culture sample were taken and againcharacterized using conventional biochemical, cultural and molecular methods. Then I checkedthe antimicrobial activity of ginger alone and with soyaoil against these isolates using discdiffusion method. Result: It shows that ginger alone having good antimicrobial activity againstpseudomonas but when using after mixing with soya oil its antimicrobial activity decreasedas it was note when individually used. Conclusion: Ginger when using alone having goodantimicrobial activity then when using in combination with soya.