Open AccessSUPERDISINTEGRANT ON DISINTEGRANT AND DISSOLUTION
Author(s) -
Muhammad Fazal Hussain Qureshi,
Farya Zafar,
Huma Ali,
Kamran Hameed,
Neelam Mallick,
Sohail Khan,
Saba Ajaz Baloch
Publication year - 2016
Publication title -
the professional medical journal/the professional medical journal
Language(s) - English
Resource type - Journals
eISSN - 2071-7733
pISSN - 1024-8919
DOI - 10.29309/tpmj/2016.23.10.1716
Subject(s) - dissolution , pharmacology , medicine , chemical engineering , engineering
In tablet formulation superdisintegrants are added to accelerate the rate of tabletdeaggregation and thus enhancing the rate of tablet dissolution. In this review article we gatherthe information related to the superdisintegrants, their mechanism of actions and their impacton disintegration and dissolution processes. The easiest way to achieve quick release is to usea superdisintegrants with appropriate concentrations of excipients. Different superdisintegrantsare usually added to facilitate the tablet disintegration, thus increasing the rate of tabletdissolution.