LIVER CIRRHOSIS

Objectives: The aim behind this study was to scientifically assess the poorprognostic factors and in-hospital mortality rate in patients infected with HCV and HBV infectionwith liver cirrhosis. Study Design: Comparative hospital based study. Setting: Gastroenterologyand hepatology dedicated center, Asian Institute of Medical Sciences (AIMS), Hyderabad.Period: Thirty one months from 1st October 2012 to 31st May 2015. Patients and Methods: 419participants between the ages of 20 to 80 years including both male and female and diagnosedeither with HCV or HBV infection along with cirrhosis were included. Data were entered andanalyzed by using Statistical Package for the Social Sciences version 20.0. Results: Out of total419 patients, the mean age and S.D. of HBV patients were 41.21 ± 11.77 and HCV patientswere 50.44 ± 10.07 years. The overall mortality rate was 11.69% (N = 49) among them patientswith of HBV infection had a comparatively higher mortality rate than patients with HCV infection,13.07% and 11.07%, respectively. The most common risk factors observed in our study wereHepatorenal syndrome (41.17%) in HCV cirrhotics and hematemesis (34.37%) in HCV cirrhoticpatients. Conclusion: Our study shows that overall mortality is greater in HBV cirrhotic patientsthan with HCV cirrhotics. Poor in-hospital mortality factors vary in both HBV and HCV relatedcirrhotic patients and this discrepancy in the observation is universally observed