Open AccessPRE-ECLAMPSIA
Author(s) -
Abdul Karim Khan,
Hamzullah Khan
Publication year - 2016
Publication title -
the professional medical journal/the professional medical journal
Language(s) - English
Resource type - Journals
eISSN - 2071-7733
pISSN - 1024-8919
DOI - 10.29309/tpmj/2016.23.02.868
Subject(s) - medicine , eclampsia , leptin , body mass index , preeclampsia , inclusion and exclusion criteria , pregnancy , blood pressure , microsoft excel , obstetrics , gynecology , obesity , pathology , genetics , alternative medicine , computer science , biology , operating system
Objectives: To determine the relation of leptin, hypertension and body massindex with pre-eclampsia in the 3rd trimester of pregnancy in a hospital based study. Design:descriptive observational study. Setting: three teaching hospital of Peshawar, Khyber teachinghospital, Hayatabad medical complex and lady reading hospital Peshawar. Duration: June2012-dec 2012. Inclusion criteria: all women in their third trimester without any co-morbidity.Exclusion criteria: were all diabetic and first and 2nd trimester pregnant ladies. Procedure:relevant information on height, weight, body mass index (BMI), pulse, blood pressure and leptinwere recorded on a predesigned questionnaire prepared in accordance with the objectivesof the study. Data was analyzed in MS-Excel. Results: A total of 80 pregnant ladies included.Majority of the patients were in the age range of 17-26 years of age. Maximum number 30(37.5%)of patients were in weight ranging 66-75 kg. We observed maximum number of patients werenormotensive systolic BP 110-130mmHg (47%). About 43% of patients had BP>140mmHg upto 200mmHg. 6% had Diasatolic BP between 130-140mmHg. 23.5% had BMI>32.6. 38% hadBMI between 27.62-32.62. We observed that majority of the patients were in the leptin serumrange of 229.57-329.57. 7.75% had serum leptin level above 329 with a maximum of 829.6in one patient at top in data. Conclusion: Serum leptin level in pregnancy increases in thirdtrimester with a determined relation of serum leptin level with gestaional hypertension and preeclampsia.