Open AccessDIABETIC FOOT INFECTION
Author(s) -
Abdul Ghani Rahimoon,
Muhammad Tanveer Alam,
Muhammad Saeed Talpur
Publication year - 2015
Publication title -
the professional medical journal/the professional medical journal
Language(s) - English
Resource type - Journals
eISSN - 2071-7733
pISSN - 1024-8919
DOI - 10.29309/tpmj/2015.22.11.874
Subject(s) - medicine , diabetic foot , cloxacillin , imipenem , amikacin , clindamycin , levofloxacin , cefotaxime , klebsiella , diabetes mellitus , staphylococcus epidermidis , staphylococcus aureus , microbiology and biotechnology , antibiotic resistance , antibiotics , penicillin , bacteria , biology , biochemistry , genetics , escherichia coli , endocrinology , gene
Objectives: To determine the frequency of common bacterial isolates culturedfrom diabetic foot infection in patients with type 2 diabetes mellitus (DM) falling in Wagner’sgrade-2 and grade-3 classification of diabetic foot (DF) infection. Study Design: Descriptivestudy. Period: A six months. Setting: Dow University of health sciences and civil hospital Karachi.Methods: Completed to examine the bacterial identification in cases admitted with the infectiondiabetic foot along with gave Wagner’s evaluation 2 and 3 at tertiary care hospital Karachi.Bacteriological finding and anti-biotic affectability profiles were completed and analyzed withutilizing standard strategies. Results: Out of 115 cases, 82 (71%) were male and 23 (29%) werefemale. The mean age of patients was 51.7 ±9.45 years, mean duration of diabetes was 10.6± 4.73 years, similarly mean length of time of diabetes foot wound was 46.15±23.75 days. 45(39%) patients had Wegner’s evaluation 2 and 70 (61%) patients had Wagner’s evaluation 3. 99cases indicated with culture growth, out of which 65 (65.65%) with gram negative microbes and25 (25.25%) gram-positive microbes. The most successive bacteria’s were Proteus (35.35%),Staph. Aureus (25.25%), Klebsiella (16.16%) and Pseudomonas (15.15%). Both gram positiveand gram negative showed frequent resistance to Cloxacillin, Amoxacillin, Levofloxacin, andLinezolid, gram negative life forms likewise indicated high resistance rate to Clindamycin,Vancomycin, and Cefotaxime. Tienam (Imipenem), Sulzone (salbactam in addition tocefoperazone) and Amikacin were the best effective against gram -ve and gram +vemicrobes.Staph. Aureus and Staph. Epidermidis were profoundly susceptible to Ciprofloxacin, Ceftriaxone,Clindamycin, and Vancomycin. Conclusion: Gram negative microbes were more common thangram positive living beings. Proteus, Staph Aureus, Klebsiella and Pseudomonas aeruginosawere the most widely recognized microorganisms of DF infection. Tienam (Imipenem), Sulzone(salbactam in addition to cefoperazone), and Amikacin were best effective agents.