Open AccessSPINAL ANAESTHESIA
Author(s) -
Muhammad Yousuf,
S. A. Haider,
M. Mudassir Aziz,
Salman Waris
Publication year - 2015
Publication title -
the professional medical journal/the professional medical journal
Language(s) - English
Resource type - Journals
eISSN - 2071-7733
pISSN - 1024-8919
DOI - 10.29309/tpmj/2015.22.08.1150
Subject(s) - medicine , shivering , anesthesia , ketamine , ondansetron , midazolam , general anaesthesia , tramadol , spinal anesthesia , perioperative , sedation , randomized controlled trial , combined spinal epidural , surgery , butorphanol , nausea , analgesic
Perioperative shivering is a common problem during spinal anaesthesia. Itcauses tremendous deleterious effects on metabolism of body. Despite of re-warming andraising the ambient temperature, several drugs are under research to evaluate their preventiverole in shivering during anaesthesia like tramadol, butorphanol, midazolam, ketamine andondansetron. The present study was conducted to evaluate the effect of prophylactic low doseketamine and ondansetron for prevention of shivering during spinal anaesthesia. Objective:To compare prophylactic low dose ketamine with ondansetron for prevention of shiveringduring spinal anaesthesia in patients undergoing lower abdominal surgeries. Study Design:Randomized controlled trial. Setting: Department of Anaesthesia, Nishtar Hospital Multan.Period: November 2012 to May 2013. Material and methods: A total of 256 patients wereincluded in the study divided into two equal groups. Results: In this study basic demographicslike age, gender, mean weight and height and type of surgery patients underwent weresimilar, having no significant difference in both groups, while on comparison in both groups,the frequency of shivering revealed 4.69%(n=6) in K Group and 11.72%(n=15) in O Groupwhile remaining 95.31%(n=122) in K and 88.28%(n=113) in O Group had no findings of themorbidity, p value was calculated as 0.03, which showed significant difference. Conclusion:The result of the study concluded that prophylactic intravenous administration of low doseketamine (0.25mg/kg) is significantly more effective than ondansteron (4 mg) for prevention ofshivering during spinal anesthesia in patients undergoing lower abdominal surgeries.