PEDIATRIC SURGICAL PATIENTS

Almost all the Pediatric surgeons and most of pediatric anesthetists are adheredto traditional paed’s solution against recommendations due to fear of hypoglycaemia and notbeing aware of hyponatremia. Objective: To compare the effects of balanced salt solutionwith1% dextrose and Pead’s solution on blood glucose and sodium levels in pediatric surgicalpatients intra operatively. Study Design: Interventional quasi experimental study. Setting:Department of Anesthesia, Intensive care and pain medicine in Sheikh Zayed Medical College/Hospital Rahim Yar Khan (Pakistan). Period: December 2014 to February 2015. Methodology:60 patients were enrolled and divided into equal groups named after their respective iv fluidsi.e.‘Pead’s Solution’ & ‘RLD1’. Patients aged between 1 month and 08 years, without genderdiscrimination, with ASA 1,2 , fasted according to ASA guidelines undergoing elective surgicalprocedure general anesthesia were included in this study. Blood sampling for levels of serumsodium and glucose was done pre-operatively and 01 hour post-operatively. Results: Inimmediate post-operative period incidence of hyperglycemia was statistically higher in ‘Pead’sSolution’ group (93.3%;28/30) vs ‘RLD1’ group(10%;3/30) p=0.000. Relative risk was 9.3 in‘Pead’s Solution’ compared with ‘RLD1’ solution. Hyponatremia was statistically higher in‘Pead’s Solution’ group (56.6%; 17/30) than in‘RLD1’ group (16.6%;5/30) p=0.001. Relative riskwas 3.4 in ‘Pead’s Solution’ compared with ‘RLD1’ solution. Hypoglycemia and hypernatremiawere not found in any patient in either group. Conclusion: Our results reflected that ‘RLD1’isa better option than ‘Pead’s Solution’ as it is less likely to cause hyponatremia and doesnotcause hypoglycemia. However a large number of clinical trials in almost every teaching hospitalare required to convince pediatric surgeons and anesthetists to use evidence based solutions.