METABOLIC SYNDROME

Objective: To determine the role of gamma glutamyltransferase as a biochemicalmarker for the diagnosis of metabolic syndrome. Study Design: Cross sectional descriptivestudy. Period: One year. Setting: Department of Medicine, Liaquat University HospitalHyderabad / Jamshoro. Methods: All the patients with metabolic syndrome visited at OPD /admitted in the ward were further evaluated for serum gamma-glutamyltransferase level. Thedata was analyzed in SPSS 16 and the frequency and percentage was calculated. Results:During one year study period, total one hundred patients (23 males and 77 were females) withmetabolic syndrome were recruited and study for gamma glutamyl transferase level. The meanage ±SD for overall population was 56.84±6.52 whereas it was 48.92±5.82 and 58.61±7.73in male and female population respectively. The mean ± SD of systolic and diastolic bloodpressure (mmHg), triglycerides (mg/dl), high density lipoprotein pressure (mg/dl) and fastingblood sugar (mg/dl) in overall population was 161.20 ± 16.74 and 95.60 ± 8.34, 176.38 ±11.93, 29.44 ± 2.90 and 108.42± 6.25. The mean gamma glutamyl transferase level in overallpopulation was 86.75±7.74 while it was 84.83±5.32 and 89.52±6.84 in male and femalepopulation respectively. The gamma-glutamyltransferase was raised in 75 patients of which13 were males and 62 were females (p=0.02) and majority of patients were 50-59 year agegroup (p <0.01). Conclusions: It is concluded that GGT is a good diagnostic tool in metabolicsyndrome with statistical significant results.