FIBROID;

.. Introduction: Fibroids are the commonest benign tumors and it is estimated thatthey occur in 20-40% of women during their reproductive years. Reported risk factors consistentwith the hormonal hypothesis include premenopausal status, younger at menarche, and obesity.Reported protective factors include parity and oral contraceptive use. This study was designed togive us the burden of fibroid and factors leading to fibroid. Objectives: To determine thefrequency and factors leading to fibroid in women presenting with menorrhagia in outpatientdepartment of gynae unit-I Civil Hospital Karachi. Study design: Cross sectional study. Setting:Department of Obstetrics and Gynaecology- I, Civil Hospital, Karachi. Duration of study: Sixmonths from 12thMarch, 2011 to 11th September, 2011. Subjects and methods: A total of 121patients meeting the inclusion criteria were enrolled in study. History was taken regardingduration and severity of menorrhagia and the factors leading to fibroid including age, parity,obesity and family history, women with a weight of 50kg or more were taken as obese. If findingsconsistent with fibroid as per operational definition were found on ultrasound then it was termedas fibroid +ve. Results: Mean (±SD) age was 27.9 (±5.3) years. Frequency of fibroid wasfound in 68 (56.2%) patients with menorrhagia. Family history fibroid was found in 51 (42.1%)women out of which fibroid was found positive in 30 (58.8%) women, that was the most commonfactor leading to fibroid in this study, followed by obesity 28 (35.4%) and nulliparous 10 (25.6%).Conclusions: Frequency of fibroid was found in 56.2% patients with menorrhagia. Family historyof fibroid was most common risk factor leading to fibroid found in 58.8% women.