HELICOBACTER PYLORI

Objective: To determine the frequency of H. pylori in patients with functionaldyspepsia. Patients and methods: This six months multidisciplinary study was conducted attertiary care teaching hospital as well as at private hospital Hyderabad from February 2012 to July2012. All patients presented with history of dyspepsia were admitted and evaluated for functionaldyspepsia by performing endoscopy. After confirmation of functional dyspepsia the subjectswere further evaluated for H. pylori infection by taking the biopsy specimen, label it and sent tolaboratory for histopathological examination. The data was entered, saved and analyzed in SPSSversion 11.00. Results: During six month study period, total 100 patients with functionaldyspepsia were recruited. Majority of patients were from low socioeconomic class (78%), havehistory of spicy food intake (68%) and epigastric pain (94%). The associated symptoms observedwere nausea and vomiting (87%), anorexia (88%), early satiety (84%) and regurgitation (84%).The mean ±SD for age of patients with functional dyspepsia was 37.95±10.85. The mean age±SD of H. pylori identified patients was 35.81±7.72. Majority of the subjects was 30-40 years ofage and the male population predominant 64% (p-value 0.02, statistically significant). The H.pylori was identified in 62% of patients, of which 35 (56.5%) were males and 27(43.5%) werefemales (p-value 0.04, statistically significant) respectively.