Open AccessMENORRHAGIA;
Author(s) -
Farzana Zia,
Shahzeem Bhayani,
Rubina Hussain
Publication year - 2013
Publication title -
the professional medical journal/the professional medical journal
Language(s) - English
Resource type - Journals
eISSN - 2071-7733
pISSN - 1024-8919
DOI - 10.29309/tpmj/2013.20.05.1217
Subject(s) - medicine , coagulopathy , fresh frozen plasma , outpatient clinic , anemia , pregnancy , girl , surgery , pediatrics , gynecology , obstetrics , platelet , biology , genetics , psychology , developmental psychology
Factor VII deficiency is a rare, autosomal recessive coagulopathy that becomes symptomatic in the form of a hemorrhagicsyndrome characterized by severe life threatening bleeding. This may present in young women as severe anemia due to bleeding pervaginum. We report one such case of a 12 year old girl who presented at the gynecology outpatient department with complaints of severemenorrhagia at menarche. Her past history was consistent with episodes of profuse epistaxis and bleeding from gums. Her completeblood count showed severe anemia. Upon further investigation her prothrombin time was prolonged but her APTT was normal which wasindicative of Factor VII deficiency and was confirmed by serum assays of Factor VII. It is important to diagnose this disorder earlier in orderto avoid long term complications especially in women who may suffer from severe life threatening hemorrhage during menses orrecurrent miscarriages during pregnancy. Therefore, our patient was transfused with packed cells and fresh frozen plasma immediatelyand started on low dose oestrogen and progesterone pill along with tranexemic acid to control her symptoms.