Open AccessRENAL INVOLVEMENT IN ACUTE GASTROENTERITIS;
Author(s) -
Mirza Muhammad Ilyas Baig,
Nauman Tarif,
Fawad Ahmad Randhawa
Publication year - 2012
Publication title -
the professional medical journal/the professional medical journal
Language(s) - English
Resource type - Journals
eISSN - 2071-7733
pISSN - 1024-8919
DOI - 10.29309/tpmj/2012.19.06.2484
Subject(s) - medicine , creatinine , observational study , renal function , acute gastroenteritis , renal replacement therapy , shock (circulatory) , intensive care medicine , pediatrics
Objective: Acute renal failure is one of the important complications of acute gastroenteritis. Early intervention and proper fluidreplacement may lessen this risk. We conducted this observational study to see the renal involvement and its outcome in patients with acutegastroenteritis. Design: Observational study. Setting: This study was done in three different hospitals which are tertiary care and teachinghospitals. Period: May 2009 to September 2009. Material and Method: A total of 200 patients were included in this study who presented withacute gastroenteritis. All patients were assessed properly for their clinical examination and laboratory tests including renal functions,electrolytes and other routine tests were done and evaluated. These patients were treated either in Emergency department or indoordepartments. Only those patients were included in our study who met our inclusion criteria which was set before conducting study. Results: Atotal of 200 patients were included in our study, among them 160 were male patients and 40 were female patients. At presentation 32 (16%)patients had deranged renal functions, 18 (09%) patients had urea in range of 50-100mg/dL and creatinine in the range of 1.4-2.0mg/dL. 10(05%) patients had urea in range of 101-150mg/dL and creatinine 2.1-3.5mg/dL. 04 (02%) patients had urea in range of 151-200mg/dL andcreatinine 3.6-7.0mg/dL. 12 patients were received in hypovolemic shock at presentation. After one week of follow up most of these patientsimproved but 04 patients were deteriorated and put on renal replacement therapy. Patients who had their renal functions in normal range weredischarged from hospital and follow up of all these patients were continued for 6 months. It was observed that those patients which presentedlate had more chances of renal involvement. Conclusions: Early referral and timely management with fluids and antimicrobials may reducerisk of renal failure in patients with acute gastroenteritis.