Open AccessANALGESIC EFFICACY;
Author(s) -
Abrar Hussain Khosa,
N. A. Khan,
Haq Dad Durrani,
Zahra Wadoo
Publication year - 2012
Publication title -
the professional medical journal/the professional medical journal
Language(s) - English
Resource type - Journals
eISSN - 2071-7733
pISSN - 1024-8919
DOI - 10.29309/tpmj/2012.19.06.2470
Subject(s) - medicine , ketorolac , analgesic , diclofenac sodium , anesthesia , diclofenac , surgery , pharmacology
Aim: To compare the analgesic efficacy of a single dose preoperative intramuscular Ketorolac versus diclofenac sodium forprevention of postoperative pain after third molar surgery. Design: This Experimental comparative study. Setting: Department of Anesthesia,Pakistan Atomic Energy Commission, Al-Zahra Hospital, Geo Care, and Maryam Maternity Hospital, DG Khan. Period: October 2011 to March2012. Material and Method: Patients undergoing elective third molar surgery were randomly assigned into one of the two groups. In eachgroup, 60 patients completed the study properly. Group-I received diclofenac sodium 75 mg IM 20 min preoperatively and group-II receivedKetorolac 30 mg IM 20 min preoperatively. Result: Patient in Ketorolac group reported significantly lesser pain intensity scores in the 3rd hourpain than the Diclofenac group (p-value lesser than 0.0001). Patient also reported significantly longer mean time to rescue analgesic 7.5 hversus 4.8h (p lesser than 0.001., student t test) that is approximately 2.5 h longer duration of preventive analgesic consumption (p=0.006,student t test). Conclusions: Preoperative intramuscular injection of Ketorolac 30 mg is more effective than Diclofenac 75 mg in the preventionof post operative 3rd molar pain.