Open AccessLEUKEMIA;
Author(s) -
Miss Kalsoom,
Farah Khan,
Miss Sonia Noreen,
Muhammad Asif Javed
Publication year - 2012
Publication title -
the professional medical journal/the professional medical journal
Language(s) - English
Resource type - Journals
eISSN - 2071-7733
pISSN - 1024-8919
DOI - 10.29309/tpmj/2012.19.05.2396
Subject(s) - medicine , hyponatremia , hyperkalemia , cancer , gastroenterology , leukemia , analysis of variance , age groups , significant difference , sodium , demography , chemistry , organic chemistry , sociology
The present work was undertaken to analyze qualitatively the serum electrolyte (K+, Na+, Mg2+, PO43- and Cl-) levels byphotometric analysis in cancer patients as compared to non-cancer individuals. An understanding of the mechanisms involved in diseasepathogenesis is paramount for prevention and treatment in cancer patients. Material and Methods: Total 120 blood samples were collected foranalysis randomly which were divided into two groups as A (leukemia patients) and B (normal individuals) having 60 in each. Both of thesegroups were further sub-divided (20 each) into three age groups (20-35, 36-50 and 51-70) A1, B1, A2, B2, A3, B3 respectively. Results: Asignificant (p 0.05) interaction with the age limits. However a significant decrease (P<0.05) in the levels of Mg2+, PO43- and Cl- (hypomagnesia,h pophosphatemia and hypochloridemia respectively) was recorded in group B as compared to group A having independency of age limits.Conclusion: Low serum Na+ (hyponatremia) was observed in Group B3 as compared to Group A3 (51-70) except the age limits (20-35 and 36-50) which showed a non significant interaction with this decreased level of sodium. The data was statistically analyzed by ANOVA and a highlysignificant (P< 0.05) difference was obtained between both of the groups.