Open Access
HDV INFECTION IN HBV INFECTED INDIVIDUALS
Author(s) -
Ghulam Shabir Shaikh,
Akbar Ali Soomro,
Nisar Ahmed Shaikh,
Ghulam Murtaza Pathan,
Abdul Majeed Chhutto,
Zameer Ahmed Shaikh
Publication year - 2012
Publication title -
the professional medical journal/the professional medical journal
Language(s) - English
Resource type - Journals
eISSN - 2071-7733
pISSN - 1024-8919
DOI - 10.29309/tpmj/2012.19.04.2281
Subject(s) - medicine , virology , hepatitis d virus , hepatitis b virus , virus , hbsag
Objective: To determine the status of HDV infection in HBV infected individuals at Larkana. Duration & place of study: This is alaboratory based retrospective study conducted at Molecular Laboratory HPCP-CMI Central laboratory CMC Hospital City block Larkana fromOctober 2010 to September 2011. Material & methods: During the study period all the serum samples in which the HBV DNA was qualitativelydetected werefurther processed for HDV RNA detection by the method of Real time PCR. Result: During the study period a total of 1564 HBVDNA detected serum samples were processed for HDV RNA detection. The males were 1078 (69.0%) and females 486 (31.0%). The age wereranged between 15 to 73 years. Out of the 1564 HBV DNA detected serum samples, the HDV RNA was detected in 865 (55.31%) and notdetected in 699 (44.69%) individuals. Conclusions: This study showed 55.3% HDV infection in the HBV infected patient. Hence, to formulatethe treatment option and to predict the response of treatment it is necessary that every HBV infected case should be processed for HDV RNAdetection.