Open AccessDIABETIC FOOT INFECTIONS
Author(s) -
Ayaz Gul,
Javid Iqbal,
Zia Uddin Afridi
Publication year - 2012
Publication title -
the professional medical journal/the professional medical journal
Language(s) - English
Resource type - Journals
eISSN - 2071-7733
pISSN - 1024-8919
DOI - 10.29309/tpmj/2012.19.04.2261
Subject(s) - medicine , diabetic foot , staphylococcus aureus , meropenem , linezolid , antibiotic sensitivity , pseudomonas aeruginosa , antibiotics , methicillin resistant staphylococcus aureus , diabetes mellitus , foot (prosody) , antibiotic resistance , vancomycin , microbiology and biotechnology , bacteria , linguistics , philosophy , endocrinology , biology , genetics
Objective: The objective of this study is to know the frequency of methicillin resistant Staphylococcus aureus and its antibioticsensitivity in diabetic foot infections in our setup. Design: Cross sectional descriptive study. Setting: Surgical Department, Khyber TeachingHospital, Peshawar. Period: January 2008 to January 2010. Materials and Methods: A total of 84 patients, including 64 males and 20 females.Patient's identity, age, gender and the bacterial isolate on culture and sensitivity report were noted on a standardized proforma and analyzed onSPSS version 16.0. Patients of 18 years and both gender with type I & II Diabetes mellitus, diabetic foot ulcers of Wagner Classification SystemGrade 1 to 5 of 3 weeks duration, with infection and with no evidence of healing were enrolled in the study. Results: The overall mean age ofpatients was 60.8 years + 6.5SD with 9.2 + 0.5% HbA1c level. Frequency of methicillin resistant Staphylococcus aureus was 28.57%. Methicillinsensitive Staphylococcal aureus (51.19%), Pseudomonas aeruginosa (48.80%) and Escherichia coli (46.42%) were the common organismcultured. Methicillin resistant Staphylococcus aureus showed 100% sensitivity to Vancomicin, Linezolid, Meropenem, Imepenem andPipracillin/tazobactam. Conclusions: There is an alarming trend of increase in methicillin resistant Staphylococcus aureus because ofindiscriminate use of antibiotics in our set up which should be discouraged and a detailed knowledge of bacterial susceptibility to antimicrobialagents is necessary.