Open AccessPREGNANCY INDUCED HYPERTENSION;
Author(s) -
Adeel Aslam,
Wasima Talat,
Aneel Aslam
Publication year - 2007
Publication title -
the professional medical journal/the professional medical journal
Language(s) - English
Resource type - Journals
eISSN - 2071-7733
pISSN - 1024-8919
DOI - 10.29309/tpmj/2007.14.01.3619
Subject(s) - medicine , caesarean section , pregnancy , regimen , perioperative , methyldopa , anesthesia , drug , surgery , obstetrics , blood pressure , pharmacology , genetics , biology
Objective: To assess the stress response in severe pregnancy induced hypertensive patients on different drug regimen during preoperative and postoperative period. Sample size: 40 patients. Study Design: Comparative study. Place: CMH Kharian and WT Obgyne (Pvt) Ltd.Multan. Duration: June 2004 to January 2005. Patients and Methods: 40 patients of severe pregnancyinduced hypertensives were induced in this study. 20 patients were placed on a single standard antihypertensivei.e. alpha methyldopa and 20 were put on a combination of alpha methyldopa with long actingnifedipine or amlodipine. Both these groups underwent caesarean section. The stress response in both thesegroups was carefully analyzed and compared with a special note on any untoward effect on the mother orfetus. Results: The results from this trial clearly demonstrated that patients on combined drug therapyshowed better stress response during perioperative and postoperative period. Conclusion: In severe PIHpatients undergoing caesarean section good feto-maternal outcome was obtained on combinationantihypertensive drug therapy as compared to patients receiving single anti-hypertensive drug.