Open AccessMorphological diversity of vulvar lichen sclerosus
Author(s) -
Ю. А. Кузьменко-Москвина,
Т. А. Бич,
З. Н. Брагина
Publication year - 2019
Publication title -
vescì nacyânalʹnaj akadèmìì navuk belarusì. seryâ medycynskìh navuk
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.138
H-Index - 1
eISSN - 2524-2350
pISSN - 1814-6023
DOI - 10.29235/1814-6023-2019-16-3-357-364
Subject(s) - lichen sclerosus , vulva , pathology , papillomatosis , mucocutaneous zone , dermatology , precancerous condition , biopsy , medicine , vulvar diseases , disease , cancer
Vulvar lichen sclerosus (LS) is a common chronic mucocutaneous disease, which is usually underdiagnosed and tend to progress without adequate treatment. Morphological characteristics of vulvar LS with unusual histological features. Vulvar biopsy material ( n = 83) with morphologically diagnosed LS was examined histologically and statistically. Often saw-toothed modification of the epithelium, fibrinoid necrosis, cytoid bodies, satellite cell necrosis, hemorrhages, papillomatosis, milia, predominantly plasma cell inflammatory infiltrate, lymphoid follicles, elastosis, angiokeratoma-like vasculare change were found on the background vulvar LS. Saw-tooth epidermal change, multiple cytoid bodies and satellite cell necrosis are histological features of LS described for the first time in this study, the former being a frequent presentation of vulvar LS. The mentioned above histological changes cannot appear as features in favor of lichen planus in the differential diagnosis of these diseases.