Open AccessFunctional state of the heart, perxifcation oxidation of proteins and the activity of antioxidant enzymes in the blood of sexually nature rats when introducing food supplements
Author(s) -
Р. Н. Ясюченя,
С. Б. Кондрашова,
Т. М. Лукашенко
Publication year - 2019
Publication title -
vescì nacyânalʹnaj akadèmìì navuk belarusì. seryâ medycynskìh navuk
Language(s) - English
Resource type - Journals
eISSN - 2524-2350
pISSN - 1814-6023
DOI - 10.29235/1814-6023-2019-16-2-226-233
Subject(s) - tartrazine , lipid peroxidation , antioxidant , medicine , chemistry , glutamate receptor , sodium glutamate , endocrinology , heart rate , sodium , fowl , blood pressure , biochemistry , biology , raw material , paleontology , receptor , organic chemistry
The bioelectric activity of the heart, pro- and antioxidant processes in the blood of adult rats after the introduction of dietary supplements: glutamate and sodium benzoate, dye tartrazine were investigated. Consumption of sodium glutamate, sodium benzoate, tartrazine, each individually, by adult rats leads to a breakdown in a heart rate, a decrease in the duration of electrical diastole of the heart, a distortion of the P -wave potential, an increase in heart rate variability, which indicates the increased activity of cholinergic nerve fibbers involved in the regulation of the cardiac activity. In sexually mature animals, the consumption of sodium glutamate does not aect the equilibrium state in the peroxidation system – the antioxidant protection in the blood, while dye tartrazine, which is consumed with food for a long time, initiates the process of protein peroxidation and causes to suppress in the blood of sexually mature animals.