Open AccessSynthesis of S-aminoalkyl derivatives of 1,2,4-triazino[5,6-b]indole
Author(s) -
Д. В. Лопатик,
З. И. Куваева,
В. Э. Найденов,
О. М. Бондарева,
L. Yu. Tychinskaya
Publication year - 2021
Publication title -
vescì nacyânalʹnaj akadèmìì navuk belarusì. seryâ hìmìčnyh navuk
Language(s) - English
Resource type - Journals
eISSN - 2524-2342
pISSN - 1561-8331
DOI - 10.29235/1561-8331-2021-57-3-294-299
Subject(s) - indole test , chemistry , stereochemistry
Condensed indole derivatives of the 1,2,4-triazino[5,6-b]indole group show high biological activity and are of interest for the development of pharmaceuticals that have antihypoxic and antisurditant effects. By S-aminoalkylation reactions on a thione group, S-aminoalkyl derivatives of 1,2,4-triazino[5,6-b]indole-3-thione that were subject to hydrobromination in order to obtain the form of hydrobromides were synthesized, isolated and characterized.