Open AccessSynthesis and cardioprotective effectiveness of arginine succinates
Author(s) -
Д. В. Лопатик,
З. И. Куваева,
О. М. Бондарева
Publication year - 2020
Publication title -
vescì nacyânalʹnaj akadèmìì navuk belarusì. seryâ hìmìčnyh navuk
Language(s) - English
Resource type - Journals
eISSN - 2524-2342
pISSN - 1561-8331
DOI - 10.29235/1561-8331-2020-56-2-181-186
Subject(s) - arginine , succinates , pharmacology , drug , chemistry , medicine , biochemistry , amino acid
The synthesis was developed and physic-chemical properties of the pharmaceutical substance the di-L-arginine succinate were determined. Its cardioprotective effectiveness in cases of ischemic-reperfusion injury of the myocardium was demonstrated in experiments on rats. The substance was used to obtain the drug Inokardin of cardioprotective action.