Open AccessSynthesis and properties of magnetic microspheres based on magnetite and hydrophilic polymers
Author(s) -
К. В. Лазнев,
Е. Е. Шумская,
В. Е. Агабеков
Publication year - 2020
Publication title -
vescì nacyânalʹnaj akadèmìì navuk belarusì. seryâ hìmìčnyh navuk
Language(s) - English
Resource type - Journals
eISSN - 2524-2342
pISSN - 1561-8331
DOI - 10.29235/1561-8331-2020-56-2-135-142
Subject(s) - polyvinyl alcohol , glutaraldehyde , chitosan , superparamagnetism , materials science , gelatin , magnetite , chemical engineering , polymer , microsphere , carboxymethyl cellulose , magnetic nanoparticles , cationic polymerization , sonication , biopolymer , polymer chemistry , chemistry , chromatography , nanoparticle , nanotechnology , magnetization , composite material , organic chemistry , physics , quantum mechanics , magnetic field , engineering , metallurgy , sodium
Using emulsification technique, magnetic microspheres (MMS) were prepared from solutions of alginate, pectin, gelatin, chitosan and polyvinyl alcohol. Index of polidispersity of the microspheres was ≤ 0.1. The microspheres from gelatin, chitosan and polyvinyl alcohol covalently crosslinked with glutaraldehyde were resistant to sonication and hydrolysis at room temperature in buffer solution with pH 7.4. The microspheres containing superparamagnetic magnetite particles demonstrated no residual magnetization. After modification, chitosan and polyvinyl alcohol MMS were used for immunomagnetic separation of cells and germs.