Open AccessSynthesis of acyl derivatives of thiazolo[5.4-b]indole
Author(s) -
Д. В. Лопатик,
З. И. Куваева,
О. М. Бондарева,
В. Э. Найденов,
L. Yu. Tychinskaya
Publication year - 2019
Publication title -
vescì nacyânalʹnaj akadèmìì navuk belarusì. seryâ hìmìčnyh navuk
Language(s) - English
Resource type - Journals
eISSN - 2524-2342
pISSN - 1561-8331
DOI - 10.29235/1561-8331-2019-55-4-436-441
Subject(s) - succinic anhydride , indole test , chemistry , maleic anhydride , succinic acid , functional group , chemical modification , stereochemistry , combinatorial chemistry , organic chemistry , biochemistry , copolymer , polymer
2-Amino-4-acetylthiazolo[5,4-b]indole and its bromosubstituted analogue contain a free amino group and are initial compounds for chemical modification in order to obtain on their basis functional derivatives having high therapeutic activity. By the interaction of these 2-aminо-4-acetylthiazolo[5,4-b]indoles with succinic and maleic anhydrides, the corresponding imides and amides were obtained, which are of interest for use in order to create on their basis antihypoxic and actoprotective agents.