Open AccessStructural and physico-chemical transformations of modified with epoxy resin pericardia implants
Author(s) -
А. А. Гайдаш,
А. И. Кулак,
К В Дроздовский,
В. В. Казбанов,
В. К. Крутько,
Ольга Николаевна Мусская,
Ю И Линник,
К. В. Скроцкая
Publication year - 2019
Publication title -
doklady nacionalʹnoj akademii nauk belarusi
Language(s) - English
Resource type - Journals
eISSN - 2524-2431
pISSN - 1561-8323
DOI - 10.29235/1561-8323-2018-62-6-703-711
Subject(s) - pericardium , calcification , materials science , membrane , epoxy , ethylene glycol , chemistry , anatomy , biomedical engineering , pathology , composite material , medicine , biochemistry , surgery , organic chemistry
Bovine pericardium samples modified with ethylene glycol diglycidyl ether, designed for surgical correction of congenital heart defects and large blood vessels, were studied by scanning electron microscopy, X-ray diffraction, IR spectroscopy, and differential thermal analysis. It was found that the initial samples of pericardium, before implantation, contain sites of disorganization of the collagen matrix, fragile fracture of collagen fibrils and destruction of the interstitial membranes promoting the penetration of immunocytes into the deep layers of the pericardium. Ossifying calcification with amorphized hydroxyapatite deposition and bone tissue formation as well as multiple erosions and hypertrophic proliferation in the endothelial membrane were detected in the implantation pericardium samples.