Open Access<em>Lactobacillus plantarum</em> FRT4 alleviated obesity by modulating gut microbiota and liver metabolome in high-fat diet-induced obese mice
Author(s) -
Hongbo Cai,
Zhiguo Wen,
Lulu Zhao,
Dali Yu,
Kun Meng,
Peilong Yang
Publication year - 2022
Publication title -
food and nutrition research/food and nutrition research. supplement
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.041
H-Index - 37
eISSN - 1654-6628
pISSN - 1654-661X
DOI - 10.29219/fnr.v66.7974
Subject(s) - gut flora , lactobacillus plantarum , triglyceride , bacteroides , probiotic , biology , lipid metabolism , fatty liver , metabolome , metabolomics , choline , lactobacillus , endocrinology , medicine , cholesterol , biochemistry , metabolite , lactic acid , bacteria , bioinformatics , fermentation , genetics , disease
Obesity has become a global epidemic recognized by the World Health Organization. Probiotics supplementation has been shown to contribute to improve lipid metabolism. However, mechanisms of action of probiotics against obesity are still not clear. Lactobacillus plantarum FRT4, a probiotic previously isolated from a kind of local yogurt, had good acid and bile salt tolerance and lowered cholesterol in vitro .