Open AccessD-allulose ameliorates adiposity through the AMPK-SIRT1-PGC-1α pathway in HFD-induced SD rats
Author(s) -
Geum-Hwa Lee,
Cheng Peng,
Hwa Young Lee,
Seon-Ah Park,
TheHiep Hoang,
Jung Hyun Kim,
Soonok Sa,
Go-Eun Kim,
Jung-Sook Han,
Han-Jung Chae
Publication year - 2021
Publication title -
food and nutrition research/food and nutrition research. supplement
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.041
H-Index - 37
eISSN - 1654-6628
pISSN - 1654-661X
DOI - 10.29219/fnr.v65.7803
Subject(s) - ampk , medicine , endocrinology , adipogenesis , adipose tissue , adipocyte , amp activated protein kinase , chemistry , diet induced obese , obesity , phosphorylation , insulin resistance , protein kinase a , biochemistry
Adiposity is a major health-risk factor, and D-allulose has beneficial effects on adiposity-related metabolic disturbances. However, the modes of action underlying anti-hyperglycemic and hypolipidemic activity are partly understood.